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The Francis Crick Papers

Title:
Structure of Small Viruses pdf (531,492 Bytes) ocr (18,830 Bytes)
Structure of Small Viruses
Description:
Renewing their collaboration during Watson's return to the Cavendish laboratory in the fall of 1955, Watson and Crick in this article laid out a theory for explaining why all plant viruses whose structure had been studied up to that time were very similar in shape, either rod-shaped (cylindrical) or spherical. In developing their theory they once again benefited from their complementary expertise, namely Crick's extensive knowledge of X-ray crystallography and Watson's previous studies with tobacco mosaic virus and ribonucleic acid. They proposed that plant viruses consistently took one of two shapes because the two chemical components of which they were made up, ribonucleic acid surrounded by a large number of identical protein subunits, were assembled according to a general plan that was determined by "symmetry elements," structural requirements imposed by the shape of each protein subunit and by the angles of the bonds they formed with the ribonucleic acid core.
Item is a photocopy.
Number of Image Pages:
3 (531,492 Bytes)
Date:
1956-03-10 (March 10, 1956)
Creator:
Crick, Francis
Watson, James D.
Source:
Periodical: Crick, Francis, and James D. Watson. "Structure of Small Viruses." Nature 177, 4506 (10 March 1956): 473-475. Article. 3 Images.
Publisher:
Nature Publishing Group
Rights:
Reproduced with permission of the Nature Publishing Group.
URL: http://www.nature.com/nature/Exit
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Exhibit Category:
Defining the Genetic Coding Problem, 1954-1957
Unique Identifier:
SCBBZN
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Folder: [Selected articles collected by NLM]
Metadata Last Modified Date:
2010-12-13
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