In this letter to the editor of Nature Crick cast doubt on the contention by two researchers at King's College that certain
amino acids could bond directly to their codons (the triplet of bases of messenger RNA that specify a particular amino acid),
without the intervention of messenger RNA. He drew on stereochemistry, the chemical theory that deals with the relations
of atoms within the three-dimensional space of a molecule, to prove that the direct fit between amino acid and anticodon proposed
by the two researchers was not possible.
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25 February 1967
Periodical: Crick, Francis. "An Error in Model Building" [Editorial letter]. Nature 213, ([25 February 1967]): 798. Article. Letter
(correspondence). 1 Image.
[Nature Publishing Group]
Reproduced with permission of the Nature Publishing Group.