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The Arthur Kornberg Papers

Letter from Van R. Potter to Arthur Kornberg pdf (67,972 Bytes) transcript of pdf
Letter from Van R. Potter to Arthur Kornberg
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1 (67,972 Bytes)
1960-05-18 (May 18, 1960)
Potter, Van R.
University of Wisconsin. School of Medicine
Kornberg, Arthur
Original Repository: Stanford University Libraries. Department of Special Collections and University Archives. Arthur Kornberg Papers
Courtesy of Arthur Kornberg.
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Medical Subject Headings (MeSH):
Exhibit Category:
"Creating Life in the Test Tube," 1959-1970
Metadata Record Letter from Arthur Kornberg to Van R. Potter (July 5, 1960) pdf (41,430 Bytes) transcript of pdf
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Letters (correspondence)
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May 18, 1960
Dear Arthur:
In an earlier letter you suggested that I modify my DNA Model Kit so as to separate the double strand into single strands.
I finally thought of a simple way to do this utilizing the connectors I use to plug in my loudspeakers at various points in my home. These connectors are #321 Moseley 300 ohm polarized plugs available from any electronics distributor for about 10 cents per plug. They can be cemented to the colored nucleotide pairs using polystyrene cement. By using polarized connectors it is possible to completely code the pairs so that a prong = NH and a hole is a = o or -N=. By setting the connectors l/4 inch over the midline for purines and l/4 inch back of the midline for pyrimidines the coding can be complete. Moreover the pre-existing color code provides extra insurance for proper coding,
I am enclosing 4 pairs for your examination. Please use a screw-driver to separate the nucleotides if they stick at first. I also enclose a template that was used to mark the pairs so they could be properly cut into mononucleotides.
Do you think a supplemental sheet of directions would be appreciated by users of the Kit?
Please note that the nucleotides will now be strung on two wires using the holes I had drilled in the plugs, and you can now have a double strand opened at either or both ends, with new strands forming on the opened parts.
With best wishes,
Sincerely yours,
Van R. Potter
Professor of Oncology
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