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The Arthur Kornberg Papers

Title:
Letter from Henry M. Sobell to Arthur Kornberg pdf (41,083 Bytes) transcript of pdf
Letter from Henry M. Sobell to Arthur Kornberg
Description:
In their work with DNA polymerase, Kornberg and his colleagues had found that it could induce a seemingly spontaneous synthesis of an adenine-thymine polymer, without a template. This phenomenon raised a number of questions about the nature of chemical bonds in nucleotides and nucleic acids, and the exact mechanism of the polymerase. In this letter, Henry Sobell asked Kornberg about the feasibility of approaching some of these problems via crystallographic studies and included his research proposal on this topic.
Number of Image Pages:
1 (41,083 Bytes)
Date:
1964-12-31 (December 31, 1964)
Creator:
Sobell, Henry M.
Massachusetts Institute of Technology
Recipient:
Kornberg, Arthur
Source:
Original Repository: Stanford University Libraries. Department of Special Collections and University Archives. Arthur Kornberg Papers
Rights:
Reproduced with permission of Henry M. Sobell.
Exhibit Category:
"Creating Life in the Test Tube," 1959-1970
Relation:
Metadata Record Letter from Arthur Kornberg to Henry M. Sobell (April 22, 1965) pdf (79,633 Bytes) transcript of pdf
/ps/access/WHBBHC.pdf
Box Number:
32
Unique Identifier:
WHBBHD
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Transcript:
December 31, 1964
Dear Dr. Kornberg:
There have been several important developments in the field of purine-pyrimidine cocrystallization during this past year which I thought would be of special interest to you. In particular, there is a possibility that a correlation exists between the de novo synthesis of the perfectly alternating dAT copolymer and the Hoogsteen pairing configuration found in the adenine-thymine crystalline complexes. I have therefore taken the liberty of sending you a copy of my research proposal which describes this in considerable detail.
I would greatly appreciate your comments about this.
My best regards to you.
Sincerely yours,
Henry M. Sobell
Metadata Last Modified Date:
2008-10-31
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