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The Arthur Kornberg Papers

Title:
Letter from Arthur Kornberg to Salvador E. Luria pdf (45,259 Bytes) transcript of pdf
Letter from Arthur Kornberg to Salvador E. Luria
Number of Image Pages:
1 (45,259 Bytes)
Date:
1961-03-14 (March 14, 1961)
Creator:
Kornberg, Arthur
Recipient:
Luria, Salvador E.
Source:
Original Repository: Stanford University Libraries. Department of Special Collections and University Archives. Arthur Kornberg Papers
Rights:
Reproduced with permission of Arthur Kornberg.
Subject:
Medical Subject Headings (MeSH):
Enzymes
DNA
Exhibit Category:
"Creating Life in the Test Tube," 1959-1970
Box Number:
31
Unique Identifier:
WHBBHT
Document Type:
Letters (correspondence)
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Transcript:
March 14, 1961
Dear Salva:
I have enclosed a copy of the abstract that will appear in this year's Federation Proceedings. Since it was submitted we have been able to separate the phage polymerase from the coli polymerase on a phosphocellulose column. The separation is very decisive since the coli enzyme is eluted completely with a much weaker buffer and long before the phage polymerase comes off the column. Another item of interest is that under conditions suitable for extensive net DNA synthesis with the coli enzyme (10- to 20-fold), the phage polymerase does not maintain the reaction beyond DNA increase of 50% at the most. We are trying to figure out now just why the reaction stops so early and abruptly and hope to learn in due course why the phage polymerase requires a "single-stranded" primer.
Have a good time in Israel; our warmest regards to you and Zella.
Sincerely,
Arthur Kornberg
Metadata Last Modified Date:
2008-10-31
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