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The Edward D. Freis Papers

Title:
A Double Blind Control Study of Antihypertensive Agents: I. Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglionic Blocking Agents, Chlorisondamine, Mecamyamine, and Pentolinium Tartrate pdf (2,061,210 Bytes) ocr (69,365 Bytes)
A Double Blind Control Study of Antihypertensive Agents: I. Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglionic Blocking Agents, Chlorisondamine, Mecamyamine, and Pentolinium Tartrate
Description:
In 1956, Freis and a group of physicians in several Veterans Administration hospitals organized a cooperative study group to evaluate antihypertensive agents under well-controlled conditions. In this first of three articles, they reported that various therapeutic regimens were compared in a double-blind control study on 326 hypertensive patients, 232 of whom completed a full year of treatment. The group found that a combination of reserpine (a ganglionic-blocking agent) and hydralazine (a vasodilator) was far more effective than placebos or reserpine alone.
Number of Image Pages:
16 (2,061,210 Bytes)
Date:
1960-07 (July 1960)
Creator:
Veterans Administration Cooperative Study Group on Antihypertensive Agents
Source:
Periodical: Veterans Administration Cooperative Study Group on Antihypertensive Agents. "A Double Blind Control Study of Antihypertensive Agents: I. Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglionic Blocking Agents, Chlorisondamine, Mecamyamine, and Pentolinium Tartrate." Archives of Internal Medicine 106, (July 1960): 81-96. Article. 16 Images.
Publisher:
American Medical Association
Rights:
This item is in the public domain. It may be used without permission.
Subject:
Medical Subject Headings (MeSH):
Hypertension
Antihypertensive Agents
Reserpine
Hydralazine
Ganglionic Blockers
Exhibit Category:
The Veterans Administration Hospital and Georgetown University School of Medicine, 1949-1964
Relation:
Metadata Record Double Blind Control Study of Antihypertensive Agents: II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate (August 1962) pdf (1,046,052 Bytes) ocr (31,397 Bytes)
/ps/access/XFBBDZ.pdf
Metadata Record Double Blind Control Study of Antihypertensive Agents: III. Chlorothiazide Alone and in Combination with Other Agents; Preliminary Results (August 1962) pdf (822,988 Bytes) ocr (26,216 Bytes)
/ps/access/XFBBFB.pdf
Box Number: 7
Folder Number: 14
Unique Identifier:
XFBBDY
Document Type:
Articles
Language:
English
Format:
application/pdf
image/tif
Physical Condition:
Good
Series: Writings and Lectures, 1942-2002
SubSeries: Articles and Essays, 1942-2001
Folder: D, 1954-85
Metadata Last Modified Date:
2007-01-12
Linked Data:
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