Effect of Treatment on Morbidity in Hypertension. Veterans Administration Cooperative Study on Antihypertensive Agents: Effect
on the Electrocardiogram
This article presented more results of the Veterans Administration Cooperative Study on Antihypertensive Agents, for which
Freis received the Lasker Award in 1972. This report primarily followed up on various earlier reports that indicated that
particular electrocardiographic abnormalities associated with hypertension sometimes reverted to normal following treatment.
Since these earlier studies did not include controls, Freis's group argued that they could not provide an adequate quantitative
assessment of the benefits of antihypertensive medications. They found that hypertensive patients seldom experienced electrocardiographic
reversions following drug treatment.
Number of Image Pages:
10 (1,135,210 Bytes)
1973-09 (September 1973)
Poblete, P. F.
Kyle, Mary C.
Pipberger, H. V.
Freis, Edward D.
Periodical: Poblete, P. F., Mary C. Kyle, H. V. Pipberger, and Edward D. Freis. "Effect of Treatment on Morbidity in Hypertension.
Veterans Administration Cooperative Study on Antihypertensive Agents: Effect on the Electrocardiogram." Circulation XLVIII,
(September 1973): 481-490. Article. 10 Images.
[American Heart Association]
This item is in the public domain. It may be used without permission.
Medical Subject Headings (MeSH):
The VA Cooperative Study and the Beginning of Routine Hypertension Screening, 1964-1980
Effects of Treatment on Morbidity in Hypertension: Results in Patients with Diastolic Blood Pressures Averaging 115 through
129 mm Hg (December 11, 1967)
Effects of Treatment on Morbidity in Hypertension: II. Results in Patients with Diastolic Blood Pressure Averaging 90 through
114 mm Hg (August 17, 1970)
Effects of Treatment on Morbidity in Hypertension: III. Influence of Age, Diastolic Pressure, and Prior Cardiovascular Disease;
Further Analysis of Side Effects (May 1972)
Rebuttal: Appraisal of Antihypertensive Drug Therapy (July 1974)