Mechanism of the Antihypertensive Effects of Diuretics: Possible Role of Salt in Hypertension
In 1957, Freis was the first to announce the treatment of hypertension with the diuretic chlorothiazide. Especially when taken
in conjunction with other drugs, chlorothiazide proved extremely effective at lowering blood pressure. In this follow-up to
a paper on chlorothiazide Freis presented with Ilse Wilson in 1959, he further discussed the drug's effectiveness as well
as the role salt plays in hypertension.
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8 (906,302 Bytes)
Freis, Edward D.
Periodical: Freis, Edward D. "Mechanism of the Antihypertensive Effects of Diuretics: Possible Role of Salt in Hypertension."
Clinical Pharmacology and Therapeutics 1, 3 ([May-June 1960]): 337-344. Article. 8 Images.
C. V. Mosby Company
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Medical Subject Headings (MeSH):
The Veterans Administration Hospital and Georgetown University School of Medicine, 1949-1964
Relationship Between Plasma and Extracellular Fluid Volume Depletion and the Antihypertensive Effect of Chlorothiazide (December