The Transformation In Vitro of R Pneumococci into S Forms of Different Specific Types by the Use of Filtered Pneumococcus Extracts

Title:
The Transformation In Vitro of R Pneumococci into S Forms of Different Specific Types by the Use of Filtered Pneumococcus Extracts
Creator:
Alloway, J. Lionel
Date:
1 January 1932
Description:
Alloway published this article shortly after he joined Avery's lab. In it, Alloway demonstrated that by dissolving certain living pneumococci cells in sodium dexoycholate one could bring about transformation in vitro, rather than in laboratory mice as had previously been demonstrated. Through the process described here, he yielded the first soluble preparation of DNA, although it was not to be identified as such for 10 more years.
Periodical:
Journal of Experimental Medicine
Publisher:
Rockefeller University. Press
Location:
Box: 1. Folder: 5
Rights:
Reproduced with permission of the Rockefeller University Press.
Genre:
Articles
Subject:
Transformation, Genetic and Research Design
Format:
Text
Extent:
9 pages
Relation:
Beitrage zur Variabilitat der Pneumokokken, 1928
The Interconvertibility of 'R' and 'S' Forms of Pneumococcus, 1928
The Transformation of Pneumococcal Types In Vitro, 1930
Further Observations on the Use of Pneumococcus Extracts in Effecting Transformation of Type In Vitro, 1933
Language:
English
Legacy Source Citation:
Periodical. Alloway, J. Lionel. "The Transformation In Vitro of R Pneumococci into S Forms of Different Specific Types by the Use of Filtered Pneumococcus Extracts." Journal of Experimental Medicine 55, 1 (1 January 1932): 91-99. Article. 9 Images.. Journal of Experimental Medicine
Legacy ID:
CCAAAI
NLM ID:
101584575X5
Profiles Collection:
The Oswald T. Avery Collection
Shareable Link:
https://profiles.nlm.nih.gov/101584575X5
Story Section:
Shifting Focus: Early Work on Bacterial Transformation, 1928-1940