Title:

Antiblastic Immunity

Creator:

Avery, Oswald Theodore, 1877-1955
Dochez, A. R. (Alphonse Raymond)

Date:

January 1916

Description:

In this mildly controversial article, Dochez and Avery presented their theory of antiblastic immunity--the resistance to pneumococci as a result of the inhibition of particular pneumococcal enzymes by the serum from an infected person or animal--that promised to shed considerable light on the mechanisms by which parasitic bacteria establish themselves in animal tissue. Subsequent research conducted by others at the Rockefeller Institute determined that although antipneumococcal serum could retard the growth of pneumococci, it was not due to inhibition of enzymatic activity but the result of agglutination, which had few practical applications, effectively disproving Avery and Dochez's theory of antiblastic immunity.

Periodical:

Journal of Experimental Medicine

Publisher:

Rockefeller University. Press

Rights:

Public Domain

Genre:

Articles

Format:

Text

Extent:

8 pages

Language:

English

Legacy Source Citation:

Periodical. Dochez, A. R., and Oswald T. Avery. "Antiblastic Immunity." Journal of Experimental Medicine 23, 1 (January 1916): 61-68. Article. 8 Images.. Journal of Experimental Medicine

Legacy ID:

CCGMBJ

NLM ID:

101584575X529

Profiles Collection:

The Oswald T. Avery Collection

Shareable Link:

https://profiles.nlm.nih.gov/101584575X529

Story Section:

From Physician to Researcher: Early Laboratory Career and World War I, 1904-1919