Title:

The Soluble Specific Substance of Pneumococcus: Second Paper

Creator:

Heidelberger, Michael
Avery, Oswald Theodore, 1877-1955

Date:

August 1924

Description:

Avery's research on the specific soluble substance, or SSS, was an attempt to identify the substance that was responsible for the specific immunological reactions produced in pneumonia patients. Here, Avery and Heidelberger elaborated on their first paper (published in 1923) by indicating that they had improved the technique for the concentration and purification of SSS, and reported that distinct differences existed between the SSS of type-II and type-III pneumococci. The collaboration between Avery and Heidelberger initiated a line of research that yielded two articles, and, after Heidelberger left for Mount Sinai Hospital in 1924, several by Avery with Walther Goebel and F. H. Babers in the late 1920s.

Periodical:

Journal of Experimental Medicine

Publisher:

Rockefeller University. Press

Rights:

Reproduced from the Journal of Experimental Medicine, 1924, 40, 301-316, by copyright permission of the Rockefeller University Press.

Genre:

Articles

Format:

Text

Extent:

16 pages

Relation:

The Elaboration of Specific Soluble Substance by Pneumococcus During Growth, 1917
The Soluble Specific Substance of Pneumococcus, 1923
Immunologic Relationships of Cell Constituents of Pneumococcus, 1923

Language:

English

Legacy Source Citation:

Periodical. Heidelberger, Michael, and Oswald T. Avery. "The Soluble Specific Substance of Pneumococcus: Second Paper." Journal of Experimental Medicine 40, 3 (August 1924): 301-316. Article. 16 Images.. Journal of Experimental Medicine

Legacy ID:

CCGMHN

NLM ID:

101584575X630

Profiles Collection:

The Oswald T. Avery Collection

Shareable Link:

https://profiles.nlm.nih.gov/101584575X630

Story Section:

The Making of an Immunologist: Heidelberger's Years at the Rockefeller Institute, 1912-1927