Title:

The Transmission of Meperidine across the Human Placenta

Creator:

Burns, J. J.
Brodie, Bernard B.
Papper, E. M.
Apgar, Virginia

Date:

December 1952

Description:

Much of Apgar's research during the early 1950s focused on the effects of maternal anesthesia on the newborn child; she and other investigators asked whether anesthetic agents crossed the placenta from mother to fetus, and if so, whether the drugs endangered the baby. In this case, they found that meperidine (Demerol) did cross the placental barrier, but did not depress the respiration of the newborn.

Periodical:

American Journal of Obstetrics and Gynecology

Publisher:

C.V. Mosby Company

Rights:

Reprinted from American Journal of Obstetrics and Gynecology, 64, Apgar, Virginia, J. J. Burns, Bernard B. Brodie, and E. M. Papper, "The Transmission of Meperidine across the Human Placenta," 1368-1370, Copyright 1952, with permission from Elsevier.

Genre:

Articles

Subject:

Anesthesiology and Obstetrics

Format:

Text

Extent:

3 pages

Language:

English

Legacy Source Citation:

Periodical. Apgar, Virginia, J. J. Burns, Bernard B. Brodie, and E. M. Papper. "The Transmission of Meperidine across the Human Placenta." American Journal of Obstetrics and Gynecology 64, 6 (December 1952): 1368-1370. Article. 3 Images.. American Journal of Obstetrics and Gynecology

Legacy ID:

CPBBJN

NLM ID:

101584647X137

Profiles Collection:

The Virginia Apgar Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584647X137

Story Section:

Obstetric Anesthesia and a Scorecard for Newborns, 1949-1958