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After moving to Columbia University's College of Physicians and Surgeons, Heidelberger worked with Forrest Kendall to develop a method for determining the specific polysaccharide in type III pneumococcus by using only small amounts of the substance. A procedure that would allow scientists to identify the polysaccharide at hand would allow them to determine the pneumococcal strain present, as each type of pneumococcus possesses a unique polysaccharide capsule.
Periodical. Heidelberger, Michael, and Forrest E. Kendall. "Quantitative Studies on the Precipitin Reaction: The Determination of Small Amounts of a Specific Polysaccharide." Journal of Experimental Medicine 55, 4 (April 1932): 555-561. Article. 7 Images.. Journal of Experimental Medicine