Title:

Letter from Michael Heidelberger to Manfred M. Mayer, Johns Hopkins University

Creator:

Heidelberger, Michael

Recipient:

Mayer, Manfred M. and Johns Hopkins University

Date:

13 July 1948

Description:

In this letter to Mayer, his former graduate student and collaborator in his research on complement, Heidelberger offered comments on the draft of an article by Mayer on the kinetics (the rate and process) of hemolysis, the rupture of the membrane of red blood cells (erythrocytes) and the release of hemoglobin, caused, in Mayer's experiments, by antibodies in the form of complement-dependent lysis (rupture). Complement, a complex system of over twenty serum proteins, plays an essential enzymatic role in host defense mechanisms against invading organisms.

Location:

Box: 4. Folder: 4

Rights:

Public Domain

Genre:

Letters (correspondence)

Subject:

Complement System Proteins

Format:

Text

Extent:

1 pages

Relation:

Letter from Manfred M. Mayer, Johns Hopkins University to Michael Heidelberger, 1948

Language:

English

Legacy ID:

DHBBLK

NLM ID:

101584940X170

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X170

Story Section:

Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954