Title:

Letter from Michael Heidelberger to Hugh S. Taylor, Princeton University

Creator:

Heidelberger, Michael

Recipient:

Taylor, Hugh S. and Princeton University

Date:

7 November 1939

Description:

Heidelberger had helped to synthesize cyclooctatetraene, the next higher analog of benzene (consisting of a ring with eight carbon atoms and four double bonds), during a year of postdoctoral study (1911-12) in the laboratory of the 1915 Nobel Laureate, Richard Willstatter, at the Federal Polytechnic Institute in Zurich, Switzerland. His research with Willstatter on cyclooctatetraene was controversial, and was questioned as late as the 1940s by Hugh S. Taylor and Charles D. Hurd. Heidelberger, however, strongly defended his results, as documented in this letter, pointing out that while Taylor and Hurd showed that cyclooctatetraene resinifies and degrades at high temperatures, he had worked in cold temperatures continuously for 24 hours to synthesize a colorless liquid that was both stable and reactive. Heidelberger and Willstatter's results stood, and as a consequence of their work cyclooctatetraene became a widely used intermediate in organic chemistry.

Location:

Box: 1. Folder: 1

Rights:

Public Domain

Genre:

Letters (correspondence)

Subject:

Chemistry, Organic

Format:

Text

Extent:

1 pages

Relation:

Letter from Michael Heidelberger to Hugh S. Taylor, Princeton University, 1939
Letter from Hugh S. Taylor, Princeton University to Michael Heidelberger, 1939
Letter from Michael Heidelberger to Charles D. Hurd, Northwestern University, 1939
Letter from Charles D. Hurd, Northwestern University to Michael Heidelberger, 1939
Letter from Richard Willstatter to Michael Heidelberger, 1940

Language:

English

Legacy ID:

DHBBMF

NLM ID:

101584940X187

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X187

Story Section:

The Making of an Immunologist: Heidelberger's Years at the Rockefeller Institute, 1912-1927