Title:

Chemical Studies on Bacterial Agglutination: II. The Identity of Precipitin and Agglutinin

Creator:

Heidelberger, Michael
Kabat, Elvin Abraham, 1914-2000

Date:

May 1936

Description:

In this article, Heidelberger and his first graduate student, Elvin A. Kabat, showed that agglutination (the clumping together) and precipitation of bacterial and other antigens were not triggered by two distinct types of antibodies, as immunologists had long argued, but were two different functions of the same antibody. Agglutination of bacterial cells, they found, was a precipitin reaction on the cellular surface, and was subject to the same theory and quantitative analysis.

Periodical:

Journal of Experimental Medicine

Publisher:

Rockefeller Institute for Medical Research

Rights:

Reproduced from the Journal of Experimental Medicine, 1936, 63, 737-744 by copyright permission of the Rockefeller University Press.

Genre:

Articles

Subject:

Antigen-Antibody Reactions, Precipitins, and Agglutination

Format:

Text

Extent:

8 pages

Relation:

Chemical Studies on Bacterial Agglutination: III. A Reaction Mechanism and a Quantitative Theory, 1937

Language:

English

Legacy Source Citation:

Periodical. Heidelberger, Michael, and Elvin A. Kabat. "Chemical Studies on Bacterial Agglutination: II. The Identity of Precipitin and Agglutinin." Journal of Experimental Medicine 63, 5 (May 1936): 737-744. Article. 8 Images.. Journal of Experimental Medicine

Legacy ID:

DHBBBX

NLM ID:

101584940X19

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X19

Story Section:

Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954