Title:

Letter from A. M. Pappenheimer, Jr., University of Pennsylvania School of Medicine to Michael Heidelberger

Creator:

Pappenheimer, A. M. (Alwin Max), 1908-1995
University of Pennsylvania. School of Medicine

Recipient:

Heidelberger, Michael

Date:

23 October 1940

Description:

In this exchange of letters Heidelberger and Pappenheimer discussed hypotheses and evidence regarding the location of the sites at which antibody molecules (later shown to be Y-shaped) bind to antigens. One hypothesis, proposed by the preeminent physical chemist Linus Pauling and discussed in this letter, held that these binding sites were located at the ends of a symmetrical molecule.

Location:

Box: 5. Folder: 6

Rights:

Reproduced with permission of John R. Pappenheimer.

Genre:

Letters (correspondence)

Subject:

Antibodies

Format:

Text

Extent:

2 pages

Relation:

Letter from Michael Heidelberger to A. M. Pappenheimer, Jr., University of Pennsylvania School of Medicine, 1940

Language:

English

Legacy ID:

DHBBND

NLM ID:

101584940X207

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X207

Story Section:

Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954