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This article describes Heidelberger and Karl Landsteiner's research into hemoglobin's ability to serve as an antigen (a chemical or compound that stimulates an immunologic response, usually in the form of antibodies), an important step in understanding the antigenic properties of proteins in general. The pair concluded that while hemoglobin can stimulate antibody production, these antibodies are species-specific.
Periodical. Heidelberger, Michael, and Karl Landsteiner. "On the Antigenic Properties of Hemoglobin." Journal of Experimental Medicine 38, (October 1923): 561-571. Article. 11 Images.. Journal of Experimental Medicine