Title:

The Soluble Specific Substance of Pneumococcus: Third Paper

Creator:

Heidelberger, Michael
Avery, Oswald Theodore, 1877-1955
Goebel, Walther Friedrich, 1899-1993

Date:

October 1925

Description:

In this important article, Avery and Heidelberger continued their work on identifying the substance that caused each type of pneumococcus to elicit a unique immune response. Here, they determined that Type I and Type II pneumococcus strains contained chemically distinct polysaccharides, thus indicating that these unique polysaccharides were in fact the antigenic substance that determined the different levels of virulence among types of pneumococcus.

Periodical:

Journal of Experimental Medicine

Publisher:

Rockefeller Institute for Medical Research

Rights:

Reproduced from the Journal of Experimental Medicine, 1925, 42, 727-745 by copyright permission of the Rockefeller University Press.

Genre:

Articles

Subject:

Streptococcus pneumoniae and Pneumococcal Infections

Format:

Text

Extent:

19 pages

Relation:

The Soluble Specific Substance of Pneumococcus, 1923
The Soluble Specific Substance of Pneumococcus: Second Paper, 1924
The Soluble Specific Substance of Pneumococcus: IV. On the Nature of the Specific Polysaccharide of Type III Pneumococcus, 1926
The Soluble Specific Substance of Pneumococcus: V. On the Chemical Nature of the Aldobionic Acid from the Specific Polysaccharide of Type III Pneumococcus, 1927

Language:

English

Legacy Source Citation:

Periodical. Heidelberger, Michael, Walther F. Goebel, and Oswald T. Avery. "The Soluble Specific Substance of Pneumococcus: Third Paper." Journal of Experimental Medicine 45, 5 (October 1925): 727-745. Article. 19 Images.. Journal of Experimental Medicine

Legacy ID:

DHBBBG

NLM ID:

101584940X5

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X5

Story Section:

The "Sugar-Coated Microbe" and the Search for a Cure for Pneumonia, 1919-1929