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The Soluble Specific Substance of Pneumococcus: IV. On the Nature of the Specific Polysaccharide of Type III Pneumococcus
- Title:
- The Soluble Specific Substance of Pneumococcus: IV. On the Nature of the Specific Polysaccharide of Type III Pneumococcus
- Creator:
- Heidelberger, Michael
Goebel, Walther Friedrich, 1899-1993 - Date:
- 2 November 1926
- Description:
- Throughout the 1920s the scientific community remained skeptical of Avery and Heidelberger's work on the unique antigenic polysaccharides in type II and type III pneumococcus. Echoing prevailing beliefs among scientists that only proteins could act as antigens, critics contended that Heidelberger and Avery's polysaccharide solutions had been contaminated by proteins, and that these, not the polysaccharides, were causing the antigenic reactions. As a result, the two approached Walther Goebel, an organic chemist, in order to more specifically determine the nature of these polysaccharides and their antigenic properties. This article details their findings as to the structure and composition of the polysaccharide capsule of type III pneumococcus.
- Periodical:
- Journal of Biological Chemistry
- Publisher:
- American Society for Biochemistry and Molecular Biology
- Rights:
- Public Domain
- Genre:
- Articles
- Subject:
- Streptococcus pneumoniae, Pneumococcal Infections, and Polysaccharides
- Format:
- Text
- Extent:
- 12 pages
- Relation:
- The Soluble Specific Substance of Pneumococcus, 1923 The Soluble Specific Substance of Pneumococcus: Second Paper, 1924 The Soluble Specific Substance of Pneumococcus: Third Paper, 1925 The Soluble Specific Substance of Pneumococcus: V. On the Chemical Nature of the Aldobionic Acid from the Specific Polysaccharide of Type III Pneumococcus, 1927
- Language:
- English
- Legacy Source Citation:
- Periodical. Heidelberger, Michael, and Walther F. Goebel. "The Soluble Specific Substance of Pneumococcus: IV. On the Nature of the Specific Polysaccharide of Type III Pneumococcus." Journal of Biological Chemistry 70, 3 (2 November 1926): 613-624. Article. 12 Images.. Journal of Biological Chemistry
- Legacy ID:
- DHBBBH
- NLM ID:
- 101584940X6
- Profiles Collection:
- The Michael Heidelberger Papers
- Shareable Link:
- https://profiles.nlm.nih.gov/101584940X6
- Story Section:
- The "Sugar-Coated Microbe" and the Search for a Cure for Pneumonia, 1919-1929