Title:

The Chemical Nature of Immune Substances

Creator:

Heidelberger, Michael

Date:

1927

Description:

Heidelberger's work on the antigenic properties of pneumococcus polysaccharides was met with skepticism at first. Critics charged that his solutions had been tainted with proteins or protein-like substances, and that these were responsible for the observed antigenic effect. Heidelberger methodically responded to these charges in articles such as this, in which he presented the results of many different experiments that showed that the specific antigenic substance was not a protein, but a structurally unique polysaccharide.

Periodical:

Physiological Reviews

Publisher:

American Physiological Society (1887- )

Rights:

Reproduced with permission of the American Physiological Society.

Genre:

Articles

Subject:

Allergy and Immunology

Format:

Text

Extent:

22 pages

Language:

English

Legacy Source Citation:

Periodical. Heidelberger, Michael. "The Chemical Nature of Immune Substances." Physiological Reviews 7, 1 (1927): 107-128. Article. 22 Images.. Physiological Reviews

Legacy ID:

DHBBBK

NLM ID:

101584940X8

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X8

Story Section:

The Making of an Immunologist: Heidelberger's Years at the Rockefeller Institute, 1912-1927