Title:

Letter from D. Carleton Gajdusek, The Children's Hospital (Cincinnati, Ohio) to Michael Heidelberger

Creator:

Gajdusek, D. Carleton (Daniel Carleton), 1923-2008
Children's Hospital (Cincinnati, Ohio)

Recipient:

Heidelberger, Michael

Date:

23 March 1948

Description:

In this letter, Gajdusek described sera he had collected for studying the connection between disease, in particular nephritis (inflammation of the kidneys), and the level of complement, proteins that play an essential role in host defense mechanisms. Gajdusek hypothesized that complement levels declined with the onset of disease, and rose again during recovery. Unable to carry out the necessary titrations himself, he had left the sera with Heidelberger, in the hope that the latter would be able to carry out the appropriate experiments. Gajdusek here provides details about the processing, handling, and storage of sera in the early postwar years.

Location:

Box: 2. Folder: 23

Rights:

Reproduced with permission of D. Carleton Gajdusek.

Genre:

Letters (correspondence)

Subject:

Complement System Proteins and Serology

Format:

Text

Extent:

2 pages

Relation:

Letter from D. Carleton Gajdusek, The Children's Hospital (Cincinnati, Ohio) to Michael Heidelberger, 1948
Letter from Michael Heidelberger to D. Carleton Gajdusek, The Children's Hospital (Cincinnati, Ohio), 1948

Language:

English

Legacy ID:

DHBBGR

NLM ID:

101584940X97

Profiles Collection:

The Michael Heidelberger Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584940X97

Story Section:

Antigens and Antibodies: Heidelberger and The Rise of Quantitative Immunochemistry, 1928-1954