The Distribution and Metabolism of Lysergic Acid Diethylamide


Title:
The Distribution and Metabolism of Lysergic Acid Diethylamide
Description:
Late in the 1950s, Axelrod became interested in the distribution, excretion, metabolization and rate of "biotransformation" of lysergic acid diethylamide (LSD) by the body. In this first of several articles on the narcotic drug, he detailed the subcellular processes involved in the transformation of LSD, determined the order of concentrations of the drug in various tissues, determined that it was almost completely metabolized by the body, and found that their were considerable differences between various animal species in the rate of biotransformation of LSD.
Extent:
10 pages
Date Issued:
14 March 1957
Creator:
Axelrod, Julius, 1912-2004, Brady, Roscoe O., Witkop, Bernhard, 1917-, and Evarts, Edward V.
Source:
Periodical. Axelrod, Julius, Roscoe O. Brady, Bernhard Witkop, and Edward V. Evarts. "The Distribution and Metabolism of Lysergic Acid Diethylamide." Annals of the New York Academy of Sciences 66, (14 March 1957): 435-444. Article. 10 Images.. Annals of the New York Academy of Sciences
Periodical:
Annals of the New York Academy of Sciences
Publisher:
New York Academy of Sciences
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of the New York Academy of Sciences. Copies of Volume 66 are available through on-demand printing, and may be ordered directly from the Academy. Copies of individual articles may be ordered directly from the Academy or through Copyright Clearance Center. and http://www.nyas.org/
Subject:
Microsomes, Lysergic Acid Diethylamide, and Metabolism
Profiles in Science ID:
HHAAAK
NLM ID:
101584577X11
Genre:
Articles
Language:
English
Format:
Text
Location:
Box: 22. Folder: 9