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In this article, the work for which was supported by a NATO post-doctoral fellowship, Marshall Nirenberg and Heinrich Matthaei reveal their stable cell-free system in which their protein synthesis studies would culminate with the landmark poly-U experiments. Here, Nirenberg and Matthaei present their finding that incorporation of amino acids into protein is dependent on the addition of ribosomal RNA preparations.
Periodical:
Biochemical and Biophysical Research Communications
Periodical. Matthaei, J. Heinrich, and Marshall W. Nirenberg. "The Dependence of Cell-Free Protein Synthesis in E. coli upon RNA Prepared from Ribosomes." Biochemical and Biophysical Research Communications 4, 6 (1961): 404-408. Article. 5 Images.. Biochemical and Biophysical Research Communications