Title:

Dual Regulation of Adenylate Cyclase by Endogenous Opiate Peptides

Creator:

Nirenberg, Marshall W.
Lampert, Arthur
Klee, Werner A.

Date:

1976

Description:

This monograph expands on the relationship between morphine and other narcotics and the enzyme adenylate cyclase, arguing that endogenous opiate peptides act as dual regulators of adenylate cyclase exactly as morphine and other conventional narcotics. As potent, receptor mediated, inhibitors of adenylate cyclase activity in homogenates of hybrid cells, these peptides also have "addiction-like" qualities.

Publisher:

Elsevier/North-Holland Biomedical Press

Rights:

Reproduced with permission of Marshall W. Nirenberg.

Genre:

Monographs
Excerpts
Proceedings

Subject:

Adenylyl Cyclases, Receptors, Opioid, and Opioid Peptides

Format:

Text

Extent:

4 pages

Language:

English

Legacy Source Citation:

Monograph. Klee, Werner A., Arthur Lampert, and Marshall W. Nirenberg. "Dual Regulation of Adenylate Cyclase by Endogenous Opiate Peptides." Opiates and Endogenous Opioid Peptides: Proceedings of the International Narcotics Research Club Meeting. Elsevier/North-Holland Biomedical Press, 1976. Pp. 153-159. Excerpt. Monograph. Proceedings. 4 Images.

Legacy ID:

JJBBND

NLM ID:

101584910X212

Profiles Collection:

The Marshall W. Nirenberg Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584910X212

Story Section:

Neuroblastoma Research, 1967-1976