Title:

Opiate Receptors as Regulators of Adenylate Cyclase

Creator:

Nirenberg, Marshall W.
Sharma, S. K. (Shail K.)
Klee, Werner A.

Date:

24 May 1975

Description:

This monograph reports on the progress of Nirenberg's neuroblastoma research. The authors find that morphine inhibits enzymatic activity and enzyme production levels. Additionally, hybrid cells show that the number of opiate receptors mediates inhibition of morphine. Results suggest that because drugs may act as enzyme inducers, recovery from the addicted state requires return of adenylate cyclase activity to normal levels.

Publisher:

Pergamon Press, Inc.

Rights:

Courtesy of Marshall W. Nirenberg.

Genre:

Monographs
Excerpts

Subject:

Adenylyl Cyclases and Receptors, Opioid, mu

Format:

Text

Extent:

6 pages

Language:

English

Legacy Source Citation:

Monograph. Klee, Werner A., Shail K. Sharma, and Marshall W. Nirenberg. "Opiate Receptors as Regulators of Adenylate Cyclase." The Opiate Narcotics, Neurochemical Mechanisms in Analgesia and Dependence. Pergamon Press, 24 May 1975. Pp. 117-122. Excerpt. Monograph. 6 Images.

Legacy ID:

JJBBNG

NLM ID:

101584910X214

Profiles Collection:

The Marshall W. Nirenberg Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584910X214

Story Section:

Neuroblastoma Research, 1967-1976