Title:

Laboratory project: "Regulation of Receptor Activity"

Creator:

Nirenberg, Marshall W.
National Heart and Lung Institute. Laboratory of Biochemical Genetics
Matsuzawa, Hiroshi

Date:

September 1976

Description:

Summary of work for this project as indicated on the report: "Evidence for a new type of PGE1 receptor coupled to cGMP accumulation was obtained. Cell lines with PGE1 receptors coupled only to cAMP were found as well as cell lines with 2 species of PGE1 receptors, one coupled to cAMP accumulation, the other to cGMP accumulation. The 2 species of PGE1 receptors also desensitize at different rates. These results show that the coupling of PGE1 to increases in cAMP and cGMP levels are clonally inherited properties which can be expressed independently."

Location:

Box: 31 of 31

Rights:

Public Domain

Genre:

Reports
Excerpts

Format:

Text

Extent:

2 pages

Relation:

Annual Report of the Laboratory of Biochemical Genetics, October 1, 1975 - September 30, 1976, 1976

Language:

English

Legacy ID:

JJBBPF

NLM ID:

101584910X232

Profiles Collection:

The Marshall W. Nirenberg Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584910X232

Story Section:

Neuroblastoma Research, 1967-1976