Title:

RNA Codewords and Protein Synthesis, II. Nucleotide Sequence of a Valine RNA Codeword

Creator:

Nirenberg, Marshall W.
Leder, Philip

Date:

1964

Description:

After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the authors use a rapid method for measuring sRNA binding to ribosomes and try to resolve some problems with ambiguous and synonymous codewords. The experimental evidence suggests the binding of specific types of sRNA to ribosomes is directed by only certain corresponding trinucleotides, making sequencing efforts more feasible in the coding process.

Periodical:

Proceedings of the National Academy of Sciences of the United States of America

Publisher:

National Academy of Sciences (U.S.)

Rights:

Reproduced with permission of Marshall W. Nirenberg.

Genre:

Articles

Subject:

RNA, RNA, Messenger, Ribosomes, and Amino Acids

Format:

Text

Extent:

8 pages

Language:

English

Legacy Source Citation:

Periodical. Leder, Philip, and Marshall W. Nirenberg. "RNA Codewords and Protein Synthesis, II. Nucleotide Sequence of a Valine RNA Codeword." Proceedings of the National Academy of Sciences of the United States of America 52, (1964): 420-427. Article. 8 Images.. Proceedings of the National Academy of Sciences of the United States of America

Legacy ID:

JJBBDM

NLM ID:

101584910X52

Profiles Collection:

The Marshall W. Nirenberg Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584910X52

Story Section:

Translating the Code of Life and the Nobel Prize, 1962-1968