Title:

Receptor-Mediated Shifts in cGMP and cAMP Levels in Neuroblastoma Cells

Creator:

Nirenberg, Marshall W.
Matsuzawa, Hiroshi

Date:

September 1975

Description:

Nirenberg's interest in neuroblastoma research defined his work by the early 1970s. In this article, neuroblastoma cells are used to examine the various responses of neurons to neurotransmitters based on differences in tissue and cell type. The experimental strategy is to use the relatively homogeneous clonal neuroblasts, which have excitable membranes and respond well to chemical and electrical stimuli, to define receptor mediated responses more clearly.

Periodical:

Proceedings of the National Academy of Sciences of the United States of America

Publisher:

National Academy of Sciences (U.S.)

Rights:

Reproduced with permission of Marshall W. Nirenberg.

Genre:

Articles

Subject:

Neuroblastoma, Receptors, Drug, Receptors, Cholinergic, Cyclic AMP, and Cyclic GMP

Format:

Text

Extent:

5 pages

Language:

English

Legacy Source Citation:

Periodical. Matsuzawa, Hiroshi, and Marshall W. Nirenberg. "Receptor-Mediated Shifts in cGMP and cAMP Levels in Neuroblastoma Cells." Proceedings of the National Academy of Sciences of the United States of America 72, 9 (September 1975): 3472-3476. Article. 5 Images.. Proceedings of the National Academy of Sciences of the United States of America

Legacy ID:

JJBBDS

NLM ID:

101584910X57

Profiles Collection:

The Marshall W. Nirenberg Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584910X57

Story Section:

Neuroblastoma Research, 1967-1976