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As part of a series of articles in this collection covering Nirenberg's work on hybrid cells, the authors in this report show that clonal hybrid cells, which are known to synthesize, store and excrete acetylcholine, form synapses with striated muscle cells in vitro. The authors conclude that the ability of hybrid cells to form synapses provides opportunities to correlate aspects of synaptogenesis with the molecular basis of developmental and electrophysiological characteristics of cells.
Periodical:
Proceedings of the National Academy of Sciences of the United States of America
Periodical. Nelson, Phillip, Clifford Christian, and Marshall W. Nirenberg. "Synapse Formation Between Clonal Neuroblastoma x Glioma Hybrid Cells and Striated Muscle Cells." Proceedings of the National Academy of Sciences of the United States of America 73, 1 (January 1976): 123-127. Article. 5 Images.. Proceedings of the National Academy of Sciences of the United States of America