Title:

Regulation of Adenylate Cyclase Activity Mediated by Muscarinic Acetylcholine Receptors

Creator:

Nirenberg, Marshall W.
Klein, William L.
Nathanson, Neil M.

Date:

April 1978

Description:

This follow-up to earlier reports on the enzyme system adenylate cyclase finds that activators of excitatory acetylcholine in hybrid cells have "both transient and long-lived effects" that may be involved in transmission across certain synapses. The experimental evidence points to an increase in enzyme release as regulated by neuroreceptors.

Periodical:

Proceedings of the National Academy of Sciences of the United States of America

Publisher:

National Academy of Sciences (U.S.)

Rights:

Reproduced with permission of Marshall W. Nirenberg.

Genre:

Articles

Subject:

Receptors, Cholinergic, Receptors, Muscarinic, Adenylyl Cyclases, Neurons, and Carbachol

Format:

Text

Extent:

4 pages

Language:

English

Legacy Source Citation:

Periodical. Nathanson, Neil M., William L. Klein, and Marshall W. Nirenberg. "Regulation of Adenylate Cyclase Activity Mediated by Muscarinic Acetylcholine Receptors." Proceedings of the National Academy of Sciences of the United States of America 75, 4 (April 1978): 1788-1791. Article. 4 Images.. Proceedings of the National Academy of Sciences of the United States of America

Legacy ID:

JJBBFB

NLM ID:

101584910X64

Profiles Collection:

The Marshall W. Nirenberg Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584910X64

Story Section:

From Neuroblastoma to Homeobox Genes, 1976-1992