Synapse Turnover: A Mechanism for Acquiring Synaptic Specificity


Title:
Synapse Turnover: A Mechanism for Acquiring Synaptic Specificity
Description:
In previous studies on synapse formation, "chick embryo retina neurons were shown to form synapses rapidly with striated muscle cells" but were transient and eventually disappeared. This report uses striated muscle cells to define the number of neurons that are able to form synapses at different stages of development and suggests that both correct and incorrect synapses are formed during normal embryonic development, with correctly matched synapses being retained.
Extent:
5 pages
Date Issued:
May 1978
Creator:
Ruffolo, Robert R., Jr (Robert R. Ruffolo Jr), Eisenbarth, George S. (George S. Eisenbarth), Thompson, Jeffrey M. (Jeffrey M. Thompson), and Nirenberg, Marshall W.
Source:
Periodical. Ruffolo, Robert R. Jr, George S. Eisenbarth, Jeffrey M. Thompson, and Marshall W. Nirenberg. "Synapse Turnover: A Mechanism for Acquiring Synaptic Specificity." Proceedings of the National Academy of Sciences of the United States of America 75, 5 (May 1978): 2281-2285. Article. 5 Images.. Proceedings of the National Academy of Sciences of the United States of America
Periodical:
Proceedings of the National Academy of Sciences of the United States of America
Publisher:
National Academy of Sciences (U.S.)
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of Marshall W. Nirenberg.
Subject:
Neuromuscular Junction and Synapses
Profiles in Science ID:
JJBBFC
NLM ID:
101584910X65
Genre:
Articles
Language:
English
Format:
Text