Kinetics of Folding of Staphylococcal Nuclease


Title:
Kinetics of Folding of Staphylococcal Nuclease
Description:
In this article, Anfinsen, Schecter, and Chen reported one of the first direct measurements of the folding of proteins to their native conformation from a disordered state by use of a stopped-flow spectrofluorometer. Understanding protein folding was seen as an essential intermediate step to obtaining the information of the genetic code for the biological function of the corresponding protein or polypeptide chain.
Extent:
2 pages
Date Issued:
6 February 1970
Creator:
Schechter, Alan N., Chen, Raymond F. (Raymond F. Chen), and Anfinsen, Christian B. (Christian Boehmer), 1916-1995
Source:
Periodical. Schechter, Alan N., Raymond F. Chen, and Christian B. Anfinsen. "Kinetics of Folding of Staphylococcal Nuclease." Science 167, (6 February 1970): 886-887. Article. 2 Images.. Science
Periodical:
Science
Publisher:
American Association for the Advancement of Science
Right Type:
Public Domain
Right Statement:
http://www.sciencemag.org/
Subject:
Protein Conformation, Protein Denaturation, and Enzymes
Profiles in Science ID:
KKBBKH
NLM ID:
101584571X152
Genre:
Articles
Language:
English
Format:
Text
Location:
Box: 27. Folder: 14