Title:

Commentary by Christian B. Anfinsen on 'Studies on the Structural Basis of Ribonuclease Activity'

Creator:

Anfinsen, Christian B. (Christian Boehmer), 1916-1995

Date:

1989

Description:

In this review of an article published decades earlier while he was at Carlsberg Laboratory, Anfinsen noted that the article was a fantastic example of how a conclusion can be reached that was wrong simply due to the "paucity of knowledge at that particular time." Anfinsen extended his overall thesis to address recent concerns over scientific "fraud," and called for some leeway for "premature incorrect conclusions." The original article, "Studies on the Structural Basis of Ribonuclease Activity," appeared in "Biochimica et Biophysica Acta" 17 (1955): 141-142, by Christian B. Anfinsen, W. F. Harrington, Aase Hvidt, Kaj Linderstrom-Lang, Martin Ottesen, and John Schellman.

Periodical:

Biochimica et Biophysica Acta

Publisher:

Elsevier Science Publishers

Location:

Box: 26. Folder: 15

Rights:

Reproduced with permission of Elsevier Science Publishers. and http://www.sciencedirect.com/

Genre:

Articles

Subject:

Ribonucleases, History of Medicine, History, 20th Century, Protein Denaturation, and Protein Conformation

Format:

Text

Extent:

2 pages

Relation:

Studies on the Structural Basis of Ribonuclease Activity, 1955
Letter from Christian B. Anfinsen to Bernard D. Davis, 1989

Language:

English

Legacy Source Citation:

Periodical. Anfinsen, Christian B. "Commentary by Christian B. Anfinsen on 'Studies on the Structural Basis of Ribonuclease Activity'." Biochimica et Biophysica Acta 1000, (1989): 197-198. Article. 2 Images.. Biochimica et Biophysica Acta

Legacy ID:

KKBBKR

NLM ID:

101584571X160

Profiles Collection:

The Christian B. Anfinsen Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584571X160

Story Section:

Protein Folding and the Thermodynamic Hypothesis, 1950-1962