Title:

Comparison of beta-Galactosidases from Normal and Operator Constitutive Strains of E. Coli

Creator:

Craven, Gary
Steers, Edward, Jr., 1937-
Anfinsen, Christian B. (Christian Boehmer), 1916-1995

Date:

October 1965

Description:

This brief article, Steers, Craven, and Anfinsen reported the results of various physical and chemical studies involving enzymatic comparisons of the lactose splitting enzyme beta-galactosidases from the "normal," or "wild type," and "operator constitutive" strains of E. coli. They determined that no detectable differences could be found between the two protein preparations, and concluded that the operator locus, the region of DNA at one end of an operon that acts as the binding site for repressor proteins, did not specify any part of the structure of the beta-galactosidase molecule.

Periodical:

Proceedings of the National Academy of Sciences of the United States of America

Publisher:

National Academy Press (U.S.)

Location:

Box: 27. Folder: 9

Rights:

Reproduced with permission of Libby Anfinsen.

Genre:

Articles

Subject:

Protein Renaturation, beta-Galactosidase, and Peptide Mapping

Format:

Text

Extent:

8 pages

Language:

English

Legacy Source Citation:

Periodical. Steers, Edward Jr, Gary R. Craven, and Christian B. Anfinsen. "Comparison of beta-Galactosidases from Normal and Operator Constitutive Strains of E. Coli." Proceedings of the National Academy of Sciences of the United States of America 54, 4 (October 1965): 1174-1181. Article. 8 Images.. Proceedings of the National Academy of Sciences of the United States of America

Legacy ID:

KKBBLC

NLM ID:

101584571X169

Profiles Collection:

The Christian B. Anfinsen Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584571X169