Title:

Studies of the Aromatic Circular Dichroism of Staphylococcal Nuclease

Creator:

Anfinsen, Christian B. (Christian Boehmer), 1916-1995
Omenn, Gilbert S.
Cuatrecasas, Pedro

Date:

November 1969

Description:

In this article, Anfinsen, Omenn, and Cuatrecasas described the circular dichroism spectra of nuclease and of performic acid-oxidized derivative. Their findings suggested that the binding of the nucleotide inhibitor altered the asymmetric environment of certain tyrosyl residues. Furthermore, through titration, a method which can determine a substance or component in a solution by the addition of a liquid reagent of a known strength until a given endpoint, they were subsequently able to determine with greater certainty several of the amino acids present in the amino chain for staphylococcal nuclease.

Periodical:

Proceedings of the National Academy of Sciences of the United States of America

Publisher:

National Academy Press (U.S.)

Location:

Box: 27. Folder: 14

Rights:

Reproduced with permission of Libby Anfinsen.

Genre:

Articles

Subject:

Binding Sites, Circular Dichroism, Deoxyribonucleases, and Ribonucleases

Format:

Text

Extent:

8 pages

Language:

English

Legacy Source Citation:

Periodical. Omenn, Gilbert S., Pedro Cuatrecasas, and Christian B. Anfinsen. "Studies of the Aromatic Circular Dichroism of Staphylococcal Nuclease." Proceedings of the National Academy of Sciences of the United States of America 64, 2 (November 1969): 923-930. Article. 8 Images.. Proceedings of the National Academy of Sciences of the United States of America

Legacy ID:

KKBBLJ

NLM ID:

101584571X174

Profiles Collection:

The Christian B. Anfinsen Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584571X174