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Dr. Sawyer was in West Africa from December 1926 to mid-June 1927, serving as director of the West African Yellow Fever Commission while Dr. Henry Beeuwkes was on leave. In this letter, he described preparations for an investigation of nearby yellow fever cases, and some experiments he and Dr. Johannes Bauer had made with leptospira bacteria, which were considered the likely causative organism of yellow fever at the time.