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This schematic drawing pictures how the genes of a transforming (cancer-causing) virus may be read, or expressed, by the infected cell's genetic machinery. The machinery includes messenger RNA (mRNA) and protein-producing structures called ribosomes. The cell depicted here is permissive, meaning a type or species of cell in which a cancer-causing virus not only triggers synthesis of a transforming protein--a protein that stimulates expression of genes controlling cell division, leading to cancerous growth--but in which the virus can replicate and from which new, complete and infectious virus particles are released (virions).
Original Repository:
University of California, San Francisco. Archives and Special Collections. Harold E. Varmus Papers
Location:
Box: 7. Folder: 5
Rights:
Reproduced with permission of the Regents of the University of California.