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This was the first report of functional brain imaging based on changes in local glucose utilization in the central nervous system of the rat visualized in autoradiographs produced with the radioactive glucose analog [14C] deoxyglucose.
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Periodical. Kennedy, Charles, Jane Jehle, Martin Reivich, F. Sharpe, Louis Sokoloff, M. H. Des Rosiers, and National Institute of Mental Health (U.S.). "Mapping of Functional Neural Pathways by Autoradiographic Survey of Local Metabolic Rate with [14C]Deoxyglucose." Science 187, 4179 (7 March 1975): 850-853. Article. 4 Images.. Science