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Daniel Nathans - Profiles in Science
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Daniel Nathans
The Daniel Nathans Papers
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The Story
Biographical Overview
Choosing Research, 1955-1962
From Phage MS2 to Tumor Virus SV40, 1962-1970
Restriction Enzymes and the "New Genetics," 1970-1980
New Directions: Growth Signals and Cellular Responses, 1980-1999
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1.
Daniel Nathans as teenager, leaning on tree stump
Date:
[ca. 1942-1945]
2.
Daniel Nathans as college student
Date:
[September 1949]
3.
Excerpt from Washington University lab notebook
Date:
28 September 1953
4.
Iron Clearance and Utilization in Rats Using a Direct Method of Counting Fe59
Date:
[ca. 1954]
5.
Effect of ACTH on Distribution of Ascorbic Acid in Rat Adrenal Gland as Determined by Direct Microchemical Analysis
Date:
[ca. 1954]
6.
Lab notebook entry from notebook "Mouse Myeloma"
Date:
[19 November - 29 December 1956]
7.
Letter from Peyton Rous to Daniel Nathans
Date:
1 April 1958
8.
The Formation of Myeloma Protein by a Mouse Plasma Cell Tumor
Date:
[1 July 1958]
9.
Purification of a Supernatant Factor That Stimulates Amino Acid Transfer from Soluble Ribonucleic Acid to Protein
Date:
[August 1960]
10.
Amino Acid Transfer from Aminoacyl-Ribonucleic Acids to Protein on Ribosomes of Escherichia Coli
Date:
[15 April 1961]
11.
Biosynthesis of the Coat Protein of Coliphage f2 by E. Coli Extracts
Date:
[15 August 1962]
12.
Puromycin Inhibition of Protein Synthesis: Incorporation of Puromycin into Peptide Chains
Date:
[15 April 1964]
13.
Bacteriophage-Specific Proteins in E. Coli Infected with an RNA Bacteriophage
Date:
[December 1966]
14.
Experiment 2: Polymer Synthesis After Infection
Date:
[ca. 1967]
15.
Experiment I: Single Cycle Growth Curves
Date:
[ca. 1967]
16.
DNA-RNA Hybridization and "RNA Polymerase Purification"
Date:
[ca. 1969]
17.
SV 40 Prep
Date:
[ca. 1969]
18.
Letter from Daniel Nathans to W. Barry Wood
Date:
4 February 1969
19.
Letter from W. Barry Wood to Daniel Nathans
Date:
17 February 1969
20.
Letter from Daniel Nathans to Roy D. Schmickel
Date:
11 March 1969
21.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
[15 March 1969]
22.
SV 40 Prep
Date:
31 March 1969
23.
Letter from Ernest Winocour to Daniel Nathans
Date:
23 July 1969
24.
Letter from Daniel Nathans to Ernest Winocour
Date:
18 August 1969
25.
Lab notes on identifying SV 40 proteins in infected cells
Date:
[September-December 1969]
26.
Memorandum from Lincoln Gordon to the Faculties of Medicine and Hygiene and Public Health [on The Johns Hopkins University program in the Allied Health Sciences]
Date:
13 October 1969
27.
Memorandum from Daniel Nathans to W. Barry Wood
Date:
12 November 1969
28.
Memorandum from W. Barry Wood to David E. Rogers
Date:
18 November 1969
29.
Daniel Nathans sitting in his lab
Date:
[ca. 1970s]
30.
Daniel Nathans in cold lab
Date:
[ca. 1970s]
31.
Lab notes on determining fragments made by Hind on SV 40 DNA
Date:
[24-28 November 1970]
32.
Letter from David C. Ward to Daniel Nathans
Date:
13 January 1971
33.
Letter from Daniel Nathans to David C. Ward
Date:
25 January 1971
34.
Letter from Daniel Nathans to David C. Ward
Date:
22 February 1971
35.
Lab notes on transformation of BALB 3T3
Date:
[9-21 March 1971]
36.
Letter from David C. Ward to Daniel Nathans
Date:
16 March 1971
37.
Letter from Daniel Nathans to David C. Ward
Date:
24 June 1971
38.
Letter from David C. Ward to Daniel Nathans
Date:
2 August 1971
39.
Lab notes of electron microscopic images of E. coli B DNA
Date:
9 September 1971
40.
Letter from Ernest Winocour to Daniel Nathans
Date:
4 November 1971
41.
Specific Cleavage of Simian Virus 40 DNA by Restriction Endonuclease of Hemophilus Influenzae
Date:
December 1971
42.
Letter from Daniel Nathans to Ernest Winocour
Date:
1 December 1971
43.
Daniel Nathans with faculty of the Department of Microbiology at Johns Hopkins University School of Medicine
Date:
[ca. 1972]
44.
Letter from Maxine Singer to Daniel Nathans
Date:
11 February 1972
45.
Letter from Daniel Nathans to Maxine Singer
Date:
1 March 1972
46.
Letter from Maxine Singer to Daniel Nathans
Date:
14 March 1972
47.
Letter from Ernest Winocour and Maxine Singer to Daniel Nathans
Date:
4 July 1972
48.
Letter from Daniel Nathans to Ernest Winocour and Maxine Singer
Date:
11 July 1972
49.
Letter from Kathleen J. Danna to Daniel Nathans
Date:
31 October 1972
50.
Bidirectional Replication of Simian Virus 40 DNA
Date:
November 1972
51.
Lab notes on Hind endonuclease
Date:
[13-26 November 1972]
52.
Letter from Daniel Nathans to Kathleen J. Danna
Date:
29 November 1972
53.
Letter from Daniel Nathans to Ernest Winocour
Date:
5 December 1972
54.
Letter from Kathleen J. Danna to Daniel Nathans
Date:
20 January 1973
55.
Studies of SV40 DNA: VI. Cleavage of SV40 DNA by Restriction Endonuclease from Hemophilus Parainfluenzae
Date:
[February 1973]
56.
Letter from Daniel Nathans to Kathleen J. Danna
Date:
22 February 1973
57.
Letter from Ernest Winocour to Daniel Nathans
Date:
30 March 1973
58.
Letter from Larry Gold to Daniel Nathans
Date:
1 April 1973
59.
Letter from Daniel Nathans to Larry Gold
Date:
5 April 1973
60.
Letter from Paul Berg to Daniel Nathans
Date:
11 June 1973
61.
Letter from Maurice R. Hilleman to Paul Berg
Date:
10 July 1973
62.
Letter from Daniel Nathans to Paul Berg
Date:
23 July 1973
63.
Letter from David McConnell to Daniel Nathans
Date:
7 September 1973
64.
Letter from Daniel Nathans to David McConnell
Date:
9 October 1973
65.
Data on SV, JC, and BK cleavage
Date:
14 October 1973
66.
Letter from Bernard Weisblum to Daniel Nathans
Date:
16 November 1973
67.
Letter from Daniel Nathans to Bernard Weisblum
Date:
11 December 1973
68.
Letter from Ray Wu to Daniel Nathans
Date:
11 December 1973
69.
Letter from Daniel Nathans to Ray Wu
Date:
20 December 1973
70.
A Colinear Map Relating the Simian Virus 40 (SV40) DNA Segments of Six Adenovirus-SV40 Hybrids to the DNA Fragments Produced by Restriction Endonuclease Cleavage of SV40 DNA
Date:
February 1974
71.
The Isolation of Simian Virus 40 Variants with Specifically Altered Genomes
Date:
March 1974
72.
Letter from Janet E. Mertz to Daniel Nathans
Date:
9 August 1974
73.
Letter from Daniel Nathans to Janet E. Mertz
Date:
20 August 1974
74.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
27 November 1974
75.
Letter from Aaron J. Shatkin to Daniel Nathans
Date:
4 December 1974
76.
Letter from Janet E. Mertz to Daniel Nathans
Date:
20 December 1974
77.
Letter from Daniel Nathans to Janet E. Mertz
Date:
23 December 1974
78.
Letter from Neal Nathanson to Aaron J. Shatkin
Date:
27 December 1974
79.
A Transcriptional Map of the SV40 Genome in Transformed Cell Lines
Date:
[January 1975]
80.
Letter from David A. Jackson to Aaron J. Shatkin
Date:
13 January 1975
81.
Letter from Wallace P. Rowe to Aaron J. Shatkin
Date:
16 January 1975
82.
Letter from Daniel Nathans to Aaron J. Shatkin
Date:
23 January 1975
83.
Evolutionary Variants of Simian Virus 40: Cloned Substituted Variants Containing Multiple Initiation Sites for DNA Replication
Date:
[July 1975]
84.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
24 September 1975
85.
Letter from Daniel Nathans to Roy D. Schmickel
Date:
8 October 1975
86.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
[December 1975]
87.
Letter from Daniel Nathans to Wallace P. Rowe
Date:
1 December 1975
88.
Letter from Roy D. Schmickel to Ching-Juh Lai
Date:
[1976]
89.
A Molecular Approach to Carcinogenesis: Dissecting the Genome of a Small Tumor Virus
Date:
1976
90.
Letter from Paul Berg to Daniel Nathans
Date:
9 September 1976
91.
Letter from Daniel Nathans to Paul Berg
Date:
20 September 1976
92.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
29 September 1976
93.
Biological Activities of Deletion Mutants of Simian Virus 40
Date:
December 1976
94.
Letter from Ernest Winocour to Daniel Nathans
Date:
13 February 1977
95.
Letter from Daniel Nathans to Ernest Winocour
Date:
23 February 1977
96.
Letter from U.S. Representative Ray Thornton to Daniel Nathans
Date:
18 March 1977
97.
Testimony before the House Subcommittee on Science, Research, and Technology. March 30, 1977. Daniel Nathans, Professor and Director, Department of Microbiology, Johns Hopkins University School of Medicine
Date:
30 March 1977
98.
Draft of letter on recombinant DNA legislation (with edits by Daniel Nathans)
Date:
[September 1977]
99.
Letter from Paul Berg to Daniel Nathans
Date:
13 September 1977
100.
Daniel Nathans in his lab coat, gesturing with pipe
Date:
[ca. 1978-1980]
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