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Daniel Nathans - Profiles in Science
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Daniel Nathans
The Daniel Nathans Papers
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Choosing Research, 1955-1962
From Phage MS2 to Tumor Virus SV40, 1962-1970
Restriction Enzymes and the "New Genetics," 1970-1980
New Directions: Growth Signals and Cellular Responses, 1980-1999
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1.
Excerpt from Washington University lab notebook
Date:
28 September 1953
2.
Iron Clearance and Utilization in Rats Using a Direct Method of Counting Fe59
Date:
[ca. 1954]
3.
Effect of ACTH on Distribution of Ascorbic Acid in Rat Adrenal Gland as Determined by Direct Microchemical Analysis
Date:
[ca. 1954]
4.
Lab notebook entry from notebook "Mouse Myeloma"
Date:
[19 November - 29 December 1956]
5.
Letter from Peyton Rous to Daniel Nathans
Date:
1 April 1958
6.
The Formation of Myeloma Protein by a Mouse Plasma Cell Tumor
Date:
[1 July 1958]
7.
Purification of a Supernatant Factor That Stimulates Amino Acid Transfer from Soluble Ribonucleic Acid to Protein
Date:
[August 1960]
8.
Amino Acid Transfer from Aminoacyl-Ribonucleic Acids to Protein on Ribosomes of Escherichia Coli
Date:
[15 April 1961]
9.
Biosynthesis of the Coat Protein of Coliphage f2 by E. Coli Extracts
Date:
[15 August 1962]
10.
Puromycin Inhibition of Protein Synthesis: Incorporation of Puromycin into Peptide Chains
Date:
[15 April 1964]
11.
Bacteriophage-Specific Proteins in E. Coli Infected with an RNA Bacteriophage
Date:
[December 1966]
12.
Experiment 2: Polymer Synthesis After Infection
Date:
[ca. 1967]
13.
Experiment I: Single Cycle Growth Curves
Date:
[ca. 1967]
14.
DNA-RNA Hybridization and "RNA Polymerase Purification"
Date:
[ca. 1969]
15.
SV 40 Prep
Date:
[ca. 1969]
16.
Letter from Daniel Nathans to W. Barry Wood
Date:
4 February 1969
17.
Letter from W. Barry Wood to Daniel Nathans
Date:
17 February 1969
18.
Letter from Daniel Nathans to Roy D. Schmickel
Date:
11 March 1969
19.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
[15 March 1969]
20.
SV 40 Prep
Date:
31 March 1969
21.
Letter from Ernest Winocour to Daniel Nathans
Date:
23 July 1969
22.
Letter from Daniel Nathans to Ernest Winocour
Date:
18 August 1969
23.
Lab notes on identifying SV 40 proteins in infected cells
Date:
[September-December 1969]
24.
Memorandum from Lincoln Gordon to the Faculties of Medicine and Hygiene and Public Health [on The Johns Hopkins University program in the Allied Health Sciences]
Date:
13 October 1969
25.
Memorandum from Daniel Nathans to W. Barry Wood
Date:
12 November 1969
26.
Memorandum from W. Barry Wood to David E. Rogers
Date:
18 November 1969
27.
Lab notes on determining fragments made by Hind on SV 40 DNA
Date:
[24-28 November 1970]
28.
Letter from David C. Ward to Daniel Nathans
Date:
13 January 1971
29.
Letter from Daniel Nathans to David C. Ward
Date:
25 January 1971
30.
Letter from Daniel Nathans to David C. Ward
Date:
22 February 1971
31.
Lab notes on transformation of BALB 3T3
Date:
[9-21 March 1971]
32.
Letter from David C. Ward to Daniel Nathans
Date:
16 March 1971
33.
Letter from Daniel Nathans to David C. Ward
Date:
24 June 1971
34.
Letter from David C. Ward to Daniel Nathans
Date:
2 August 1971
35.
Lab notes of electron microscopic images of E. coli B DNA
Date:
9 September 1971
36.
Letter from Ernest Winocour to Daniel Nathans
Date:
4 November 1971
37.
Specific Cleavage of Simian Virus 40 DNA by Restriction Endonuclease of Hemophilus Influenzae
Date:
December 1971
38.
Letter from Daniel Nathans to Ernest Winocour
Date:
1 December 1971
39.
Letter from Maxine Singer to Daniel Nathans
Date:
11 February 1972
40.
Letter from Daniel Nathans to Maxine Singer
Date:
1 March 1972
41.
Letter from Maxine Singer to Daniel Nathans
Date:
14 March 1972
42.
Letter from Ernest Winocour and Maxine Singer to Daniel Nathans
Date:
4 July 1972
43.
Letter from Daniel Nathans to Ernest Winocour and Maxine Singer
Date:
11 July 1972
44.
Letter from Kathleen J. Danna to Daniel Nathans
Date:
31 October 1972
45.
Bidirectional Replication of Simian Virus 40 DNA
Date:
November 1972
46.
Lab notes on Hind endonuclease
Date:
[13-26 November 1972]
47.
Letter from Daniel Nathans to Kathleen J. Danna
Date:
29 November 1972
48.
Letter from Daniel Nathans to Ernest Winocour
Date:
5 December 1972
49.
Letter from Kathleen J. Danna to Daniel Nathans
Date:
20 January 1973
50.
Studies of SV40 DNA: VI. Cleavage of SV40 DNA by Restriction Endonuclease from Hemophilus Parainfluenzae
Date:
[February 1973]
51.
Letter from Daniel Nathans to Kathleen J. Danna
Date:
22 February 1973
52.
Letter from Ernest Winocour to Daniel Nathans
Date:
30 March 1973
53.
Letter from Larry Gold to Daniel Nathans
Date:
1 April 1973
54.
Letter from Daniel Nathans to Larry Gold
Date:
5 April 1973
55.
Letter from Paul Berg to Daniel Nathans
Date:
11 June 1973
56.
Letter from Maurice R. Hilleman to Paul Berg
Date:
10 July 1973
57.
Letter from Daniel Nathans to Paul Berg
Date:
23 July 1973
58.
Letter from David McConnell to Daniel Nathans
Date:
7 September 1973
59.
Letter from Daniel Nathans to David McConnell
Date:
9 October 1973
60.
Data on SV, JC, and BK cleavage
Date:
14 October 1973
61.
Letter from Bernard Weisblum to Daniel Nathans
Date:
16 November 1973
62.
Letter from Daniel Nathans to Bernard Weisblum
Date:
11 December 1973
63.
Letter from Ray Wu to Daniel Nathans
Date:
11 December 1973
64.
Letter from Daniel Nathans to Ray Wu
Date:
20 December 1973
65.
A Colinear Map Relating the Simian Virus 40 (SV40) DNA Segments of Six Adenovirus-SV40 Hybrids to the DNA Fragments Produced by Restriction Endonuclease Cleavage of SV40 DNA
Date:
February 1974
66.
The Isolation of Simian Virus 40 Variants with Specifically Altered Genomes
Date:
March 1974
67.
Letter from Janet E. Mertz to Daniel Nathans
Date:
9 August 1974
68.
Letter from Daniel Nathans to Janet E. Mertz
Date:
20 August 1974
69.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
27 November 1974
70.
Letter from Aaron J. Shatkin to Daniel Nathans
Date:
4 December 1974
71.
Letter from Janet E. Mertz to Daniel Nathans
Date:
20 December 1974
72.
Letter from Daniel Nathans to Janet E. Mertz
Date:
23 December 1974
73.
Letter from Neal Nathanson to Aaron J. Shatkin
Date:
27 December 1974
74.
A Transcriptional Map of the SV40 Genome in Transformed Cell Lines
Date:
[January 1975]
75.
Letter from David A. Jackson to Aaron J. Shatkin
Date:
13 January 1975
76.
Letter from Wallace P. Rowe to Aaron J. Shatkin
Date:
16 January 1975
77.
Letter from Daniel Nathans to Aaron J. Shatkin
Date:
23 January 1975
78.
Evolutionary Variants of Simian Virus 40: Cloned Substituted Variants Containing Multiple Initiation Sites for DNA Replication
Date:
[July 1975]
79.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
24 September 1975
80.
Letter from Daniel Nathans to Roy D. Schmickel
Date:
8 October 1975
81.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
[December 1975]
82.
Letter from Daniel Nathans to Wallace P. Rowe
Date:
1 December 1975
83.
Letter from Roy D. Schmickel to Ching-Juh Lai
Date:
[1976]
84.
A Molecular Approach to Carcinogenesis: Dissecting the Genome of a Small Tumor Virus
Date:
1976
85.
Letter from Paul Berg to Daniel Nathans
Date:
9 September 1976
86.
Letter from Daniel Nathans to Paul Berg
Date:
20 September 1976
87.
Letter from Roy D. Schmickel to Daniel Nathans
Date:
29 September 1976
88.
Biological Activities of Deletion Mutants of Simian Virus 40
Date:
December 1976
89.
Letter from Ernest Winocour to Daniel Nathans
Date:
13 February 1977
90.
Letter from Daniel Nathans to Ernest Winocour
Date:
23 February 1977
91.
Letter from U.S. Representative Ray Thornton to Daniel Nathans
Date:
18 March 1977
92.
Testimony before the House Subcommittee on Science, Research, and Technology. March 30, 1977. Daniel Nathans, Professor and Director, Department of Microbiology, Johns Hopkins University School of Medicine
Date:
30 March 1977
93.
Draft of letter on recombinant DNA legislation (with edits by Daniel Nathans)
Date:
[September 1977]
94.
Letter from Paul Berg to Daniel Nathans
Date:
13 September 1977
95.
Draft of letter on recombinant DNA legislation (with edits by Daniel Nathans)
Date:
[February 1978]
96.
Letter from Paul Berg to Daniel Nathans
Date:
6 February 1978
97.
The Recombinant DNA Act
Date:
13 February 1978
98.
Letter from Daniel Nathans to Paul Berg
Date:
14 February 1978
99.
Local Mutagenesis: A Method for Generating Viral Mutants with Base Substitutions in Preselected Regions of the Viral Genome
Date:
May 1978
100.
Letter from Oliver H. Lowry to Daniel Nathans
Date:
20 December 1978
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