Title:

Ultraviolet Irradiation of Bacteriophage during Intracellular Growth

Creator:

Luria, S. E. (Salvador Edward), 1912-1991
Latarjet, Raymond, 1911-

Date:

February 1947

Description:

In this paper, Luria and Latarjet described a subpopulation of E. coli, strain B infected with bacteriophage T2, with increased resistance to UV. They indicated that the infected bacteria initially showed a rapid increase in resistance due to increased resistance of the intracellular phage particles, possibly caused by accumulation of ultraviolet-absorbing material around the phage. With time, the resistance of infected bacteria to high doses of radiation decreases, likely indicating that, as phage multiplication proceeds, the apparent sensitivity of the intracellular phage particles returns to higher values. Luria spent the 1945-1946 academic year on leave in Cold Spring Harbor, directing a government research project on bacterial resistance to antibiotics. The research produced several papers, including this one.

Periodical:

Journal of Bacteriology

Publisher:

American Society for Microbiology

Rights:

Reproduced with permission of the American Society for Microbiology. and Reproduced with permission of the American Philosophical Society.

Genre:

Articles

Subject:

Bacteriophages and Mutagenesis

Format:

Text

Extent:

15 pages

Language:

English

Legacy Source Citation:

Periodical. Luria, Salvador E., and Raymond L. Latarjet. "Ultraviolet Irradiation of Bacteriophage during Intracellular Growth." Journal of Bacteriology 53, 2 (February 1947): 149-163. Article. 15 Images.. Journal of Bacteriology

Legacy ID:

QLBBGJ

NLM ID:

101584611X90

Profiles Collection:

The Salvador E. Luria Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584611X90

Story Section:

From Phage to Colicins, 1945-1972