Letter from Fritz Lipmann to Francis Crick


Title:
Letter from Fritz Lipmann to Francis Crick
Creator:
Lipmann, Fritz (Fritz Albert), 1899-1986
Recipient:
Crick, Francis, 1916-2004
Date:
27 November 1961
Description:
In this letter the biochemist Fritz Lipmann reported on work on the coding problem undertaken by fellow Nobel Laureate Severo Ochoa at New York University School of Medicine. Crick's contention that the code was degenerate, i.e. that more than one triplet could code for an amino acid, was borne out during the next few years, and Lipmann's doubts in this regard, expressed in his letter, were disproved. The letter also demonstrated that by 1961, most researchers had abandoned the idea that the code might be overlapping, that is, that a triplet might share a base with both the preceding and succeeding triplet.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Location:
Box: 10. Folder: PP/CRI/D/1/1/12
Rights:
Reproduced with permission of Stephen Lipmann.
Genre:
Letters (correspondence)
Subject:
Genetic Code
Format:
Text
Extent:
2 pages
Relation:
Letter from Francis Crick to Fritz Lipmann, 1961
Language:
English
Legacy Source Citation:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Legacy ID:
SCBBBV
NLM ID:
101584582X10
Profiles Collection:
The Francis Crick Papers
Story Section:
Deciphering the Genetic Code, 1958-1966