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After a visit to the laboratory of Gobind Khorana, Watson here summarized what was known of the genetic code in the spring of 1965, which triplets had been conclusively mapped to their respective amino acids and which still needed to be assigned. The 5' and the 3' end mark the opposite sides from which the two strands of the double helix of DNA run.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/