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In this letter Lwoff raised the problem that the two chains of the double helix had a different base sequence because they were complementary (and not identical), which meant that if each chain individually coded for proteins, the proteins would be different from one another.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Location:
Box: 10. Folder: PP/CRI/D/1/1/12
Rights:
Reproduced with permission of the Institut Pasteur Service des Archives.
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/