Letter from James D. Watson to Francis Crick


Title:
Letter from James D. Watson to Francis Crick
Description:
Both Crick and Watson focused on virus structure in the mid-1950s because studying viruses, in particular Tobacco Mosaic Virus (TMV) and related plant viruses, allowed them to investigate the structure and function of RNA (ribonucleic acid), which together with regular repeating units of protein makes up the molecules of which TMV consists. As the single-stranded companion molecule to DNA, RNA held obvious interest for Crick and Watson in their attempt to understand the way in which RNA specifies the synthesis of proteins, triggered whenever TMV infects a host cell.. In laying out experimental details about the structure of TMV, Watson confirmed Rosalind Franklin's finding that the strands of RNA bound the virus' hollow core: "The localization of the RNA within a central core is now a solid fact."
Extent:
4 pages
Date Created:
3 March 1955
Creator:
Watson, James D. (James D. Watson)
Recipient:
Crick, Francis, 1916-2004
Source:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of James D. Watson.
Subject:
Tobacco Mosaic Virus and RNA
Profiles in Science ID:
SCBBJM
NLM ID:
101584582X118
Genre:
Letters (correspondence)
Language:
English
Format:
Text
Location:
Box: 26. Folder: PP/CRI/D/2/45