Letter from Alexander Rich to Francis Crick


Title:
Letter from Alexander Rich to Francis Crick
Description:
Rich reported on his studies of the structure of RNA. He had found that a strand of poly-A (a synthetic strand of RNA consisting entirely of adenine), when combined with a strand of poly-U (a complementary strand consisting of uracil, which replaces the closely related thymine in RNA), spontaneously paired with poly-U to form a double helix similar to DNA. This double-helical form of RNA produced clear X-ray diffraction patterns that allowed inferences regarding the positions, angles, and bonds within the RNA molecule, which in its usual form is single-stranded and thus does not produce good diffraction images.. At the outset of his letter, Rich described his reaction to the death of Rosalind Franklin.
Extent:
4 pages
Date Created:
2 May 1958
Creator:
Rich, Alexander
Recipient:
Crick, Francis, 1916-2004
Source:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of Alexander Rich.
Subject:
Genetic Code
Profiles in Science ID:
SCBBCD
NLM ID:
101584582X17
Genre:
Letters (correspondence)
Language:
English
Format:
Text
Location:
Box: 10. Folder: PP/CRI/D/1/1/17