Letter from Francis Crick to Jerry Donohue


Title:
Letter from Francis Crick to Jerry Donohue
Creator:
Crick, Francis, 1916-2004
Recipient:
Donohue, Jerry
Date:
[ca. 15 July 1970]
Description:
In response to Donohue's argument that Fourier analysis of X-ray diffraction data collected by Maurice Wilkins and his colleagues did not rule out models of DNA with other base pairs than those posited by Watson and Crick, Crick here reviewed key concepts of crystallography and helical diffraction theory on which the debate hinged. He also cited the biochemical evidence for his and Watson's model of DNA then available. Crick came to the conclusion that Donohue's "hypothetical models of base-pairs are theoretically not to be trusted without further justification." As he had in his response to Donohue in the pages of Science, Crick in his letter once again challenged him to build models of his proposed structures, which Crick insisted was the only way by which the validity of Donohue's claims could be decided.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Location:
Box: 12. Folder: PP/CRI/D/2/11/1
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Genre:
Letters (correspondence)
Subject:
DNA and Crystallography, X-Ray
Format:
Text
Extent:
5 pages
Relation:
Letter from Francis Crick to Jerry Donohue, 1970
Letter from Jerry Donohue to Francis Crick, 1970
Language:
English
Legacy Source Citation:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Legacy ID:
SCBBMZ
NLM ID:
101584582X186
Profiles Collection:
The Francis Crick Papers
Story Section:
Embryology and the Organization of DNA in Higher Organisms, 1966-1976