Title:

Letter from Sydney Brenner to Francis Crick

Creator:

Brenner, Sydney

Recipient:

Crick, Francis, 1916-2004

Date:

24 March 1959

Description:

Brenner here reported results from his research with mutations of the phages (bacterial viruses) T2 and T4, research designed to match a mutation in the fine structure of a phage gene to changes in a protein whose synthesis the virus triggered when it infected a bacterial cell. Brenner sought to give experimental support to Crick's sequence hypothesis: that the sequence of the bases in DNA specified the order of the amino acids in the polypeptide chain of proteins.

Original Repository:

The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers

Location:

Box: 8. Folder: PP/CRI/D/1/1/2

Rights:

Reproduced with permission of Sydney Brenner.

Genre:

Letters (correspondence)

Subject:

Genetic Code

Format:

Text

Extent:

2 pages

Language:

English

Legacy Source Citation:

Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/

Legacy ID:

SCBBNV

NLM ID:

101584582X202

Profiles Collection:

The Francis Crick Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584582X202

Story Section:

Deciphering the Genetic Code, 1958-1966