Letter from Francis Crick to Sewell Champe


Title:
Letter from Francis Crick to Sewell Champe
Creator:
Crick, Francis, 1916-2004
Recipient:
Champe, Sewell
Date:
6 March 1967
Description:
Crick here responded to Champe's report of results from his research with the rII mutants of the bacterial viruses T2 (phage) which had been used since the early 1950s in genetic mapping experiments. Crick himself discussed results of research with acridine mutants of bacteriophage T2, a different family of mutants in whose study Crick's laboratory specialized and which he used to provide evidence for the three-letter composition of the genetic code. The specific experiments to which Crick referred were with acridine mutants called amber (the triplet UAA) and ochre (UAG) and with the triplet UGA, all three of which signal the end of the polypeptide chain in protein synthesis.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Location:
Box: 8. Folder: PP/CRI/D/1/1/3
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Genre:
Letters (correspondence)
Subject:
Genetic Code
Format:
Text
Extent:
2 pages
Relation:
Letter from Sewell Champe to Francis Crick, 1967
Language:
English
Legacy Source Citation:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Legacy ID:
SCBBNZ
NLM ID:
101584582X206
Profiles Collection:
The Francis Crick Papers
Story Section:
Embryology and the Organization of DNA in Higher Organisms, 1966-1976